姓名施美份
職稱教授
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電子郵件meifenshih@mail.cnu.edu.tw
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期刊論文(2005), "Preventing dyslipidemia by Chlorella pyrenoidosa in rats and hamsters after chronic high fat diet treatment.." Life Sciences, 26, 76. (SCI)
(2005), "Potential hypoglycemic effects of Chlorella in streptozotocin-induced diabetic mice." Life Sciences, 1, 77. (SCI)
(2006), "Platelet adsorption and hemolytic properties of liquid crystal/composite polymers." International Journal of Pharmaceutics, 327, 1. (SCI,)
(2006), "Improving glycogenesis in Streptozocin (STZ) diabetic mice after administration of green algae Chlorella." Life Sciences, 78, 11. (SCI,)
(2008), "Potential protective effect of fresh grown unicellular green algae component (resilient factor) against PMA- and UVB-induced MMP1 expression in skin fibroblasts." Eur J Dermatol, 18, 3. (SCI)
(2009), "The synthesis of cationic polyurethanes to study the effect of amines and structures on their DNA transfection potential.." Journal of Controlled Release, 133, 1. (SCI)
(2005), "Structural Characterization and Buffering Capacity in Relation to." Bioconjugate Chem., 16, 0. (SCI)
(2010), "A molecular pharmacology study into the anti-inflammatory actions of Euphorbia hirta L. on the LPS-induced RAW 264.7 cells through selective iNOS protein inhibition." Journal of Natural Medicines, 64, 3. (SCI)
(2010), "Effects of Combination Treatment with Dexamethasone and Mannitol on neuronal damage and survival in experimental heat stroke." Biol. Pharm. Bull., 33, 9. (SCI)
(2010), "Beneficial effects of Chlorella-11 peptide on blocking the LPS-induced macrophage activation and alleviating the thermal injury induced inflammation in rats." International Journal of Immunopathology and Pharmacology, 23, 3. (SCI)
(2010), "Attenuation of circulatory shock and cerebral ischemia injury in heat stroke by combination treatment with dexamethasone and hydroxyethyl starch." Experimental & Translational Stroke Medicine, 2, 1. (其他)
(2010), "半天筍之成分分析及毒性評估." 嘉南學報, 0, 36. (其他)
(2011), "Protective effects of Chlorella-derived peptide on UVB-induced production of MMP-1 and degradation of procollagen genes in human skin fibroblasts.." Regulatory Toxicology & Pharmacology, 1, 60. (SCI)
(2011), "Characterization of quaternized chitosan-stabilized iron oxide nanoparticles as a novel potentialmagnetic resonance imaging contrast agent for cell tracking." polymer International, 0, 60. (SCI)
(2011), "In vitro and in vivo therapeutics of beta-thujaplicin on LPS-induced inflammation in macrophages and septic shock in mice." International Journal Immunopathol pharmacology, 0, 0. (SCI)
(2011), "Bioeffects of Transient and Low-Intensity Ultrasound on Nanoparticles for a Safe and Efficient DNA Delivery." Nanomedicine & Nanotechnology, S3, 0. (其他)
(2011), "Synthesis and Evaluation of Poly(hexamethylene-urethane) and PEG-Poly(hexamethylene-urethane) and Their Cholesteryl Oleyl Carbonate Composites for Human Blood Biocompatibility." Molecules, 16, 0. (SCI)
(2012), "Preventive Effects of β-Thujaplicin Against." The American Journal of Chinese Medicine, 40, 2. (SCI)
(2012), "A one-step process in preparation of cationic nanoparticles with poly(lactide-co-glycolide)-containing polyethylenimine gives efficient gene delivery." Eur J Pharm Sci, 46, 5. (SCI)
Mei Fen Shih and Jong Yuh Cherng(2012), "Protective Effects of Chlorella-Derived Peptide Against UVC-Induced Cytotoxicity through Inhibition of Caspase-3 Activity and Reduction of the Expression of Phosphorylated FADD and Cleaved PARP-1 in Skin Fibroblasts." Molecules, 8, 17. (SCI)
Jong Yuh Cherng*, Ting Yi Hou, Mei Fen Shih, Herre Talsma, Wim E. Hennink(2013), "Polyurethane-based drug delivery systems." Int. J. Pharm., 450, 1-2. (SCI)
Mei-Fen Shih, Lih-Chi Chen, Jong-Yuh Cherng(2013), "Chlorella 11-peptide inhibits the production of macrophage-induced adhesion molecules and reduces the endothelin-1 expression and the endothelial permeability.." Marine drugs, 11, 0. (SCI)
Mei Fen Shih and Jong Yuh Cherng(2014), "Reduction of Adhesion Molecule Production and Alteration of eNOS and Endothelin-1 mRNA Expression in Endothelium by Euphorbia hirta L. Through Its Beneficial beta-Amyrin Molecule." Molecules, 19, 7. (SCI)
Mei-Fen Shih, Kuang-Hung Pan and Jong Yuh Cherng(2015), "Possible Mechanisms of Di(2-ethylhexyl)Phthalate-Induced MMP-2 and MMP-9 Expression in A7r5 Rat Vascular Smooth Muscle Cells." International journal of Molecular Sciences, 0, 16. (SCI)
施美份、吳士慧、蔡碧玲(2017), "新型長效性胰島素製劑--insulin degludec." 藥學雜誌, 33, 4. (其他)
Shih MF, Pan KH, Liu CC, Shen CR, Cherng JY(2018), "Treatment of β-thujaplicin counteracts di(2-ethylhexyl)phthalate (DEHP)-exposed vascular smooth muscle activation, inflammation and atherosclerosis progression." Regulatory Toxicology and Pharmacology, 92, 0. (SCI)
嚴淑揚、施美份(2018), "嚴重氣喘治療新藥benralizumab." 藥學雜誌, 135, 2. (其他)
Yu-Shih Lin, Wen-Huang Peng, Mei-Fen Shih,**(同第一作者序), Jong-Yuh Cherng(2020), "Anxiolytic effect of an extract of Salvia miltiorrhiza Bunge (Danshen) in mice." Journal of Ethnopharmacology, 264, 0. (SCI)
陳秋蘭、施美份(2021), "骨質疏鬆治療藥物機轉與新藥Romosozumab介紹." 藥學雜誌, 37, 2. (其他)
Hui-Chen Su, I-Jung Feng, Hung-Jen Tang, Mei-Fen Shih, Yi-Ming Hua(2022), "Comparative effectiveness of neuraminidase inhibitors in patients with influenza: A systematic review and network meta-analysis." Journal of Infection and Chemotherapy, 0, 0. (SCI)
1. Hui-Chen Su, Mei-Chuan Lee, Chia-Te Liao, "I-Jung Feng, Tsung Yu, Wei-Ting Chang, Mei-Fen Shih, and Han Siong Toh.(2022), "Recurrent Thromboembolism, Bleeding, and Mortality in Asian Patients With Venous Thromboembolism Receiving Different Oral Anticoagulants: A Nationwide Analysis.." Medicine, 0, 0. (SCI)
研討會論文(2002), "Possible mechanism of Chlorella pyrenoidosa in lowering blood glucose in STZ mice." XIVth World Congress of Pharmacology, San Francisco, USA.
(2003), "Angiotension I-converting enzyme inhibitory peptides derived from Chlorella.." European Congress of Nutrition, Rome, Italy.
(2004), "Conformational changes in polyplexes studied by ATR-FTIR as possible indicator for their transfection activity.." Pharmaceutical sciences World Congress, Kyoto, Japan.
(2004), "Preventive effects of water extract of Chlorella on MMP1 production induced by PMA and IL-1 in human skin fibroblast." Pharmaceutical sciences World Congress, Kyoto, Japan.
(2004), "Protective effects of water extract of Chlorella on short UV wave-induced cell damage in human skin fibroblast." Pharmaceutical sciences World Congress, Kyoto, Japan.
(2005), "Inhibitory effect of Chlorella-derived aqueous fraction (WEC257) on MMP I activity in normal fibroblask cell line." Bristish Pharmacology Society summer meeting, 劍橋, 英國.
(2005), "Inflammation inhibition of medical plaster extracts through a nitric oxide (NO) blocking pathway." Bristish Society of Pharmacology summer meeting, 劍橋, 英國.
(2009), "Lowering high glucose-induced adhesion molecules by lipophilic extract of Chlorella in SEVC cells." 6th Metabolic Syndrome, type II Diabetes, and Atherosclerosis Congress, 柏林, 德國.
(2009), "Prevention of endotoxin-induced shock by Chamaecyparis leaf extracts." 第24屆生物醫學聯合學術年會, 台北, 台灣.
(2008), "Ameliorate insulin resistance by aqueous extract of Chlorella." The 2nd World Congress on Controversies to Consensusin Diabetes, Obesity and Hypertension (CODHy), 巴塞隆納, 西班牙.
(2008), "Ameliorating Insulin Resistant Effects of Chlorella and Aqueous Extracts through NEFA Production." 第23屆生物醫學聯合學術研討會, 台北, 台灣.
(2007), "Potential anti-inflammation effects of lipophilic extract of Chlorella through a nitric oxide (NO)-dependent blocking pathway." 第10屆european nutrition congress, 巴黎, 法國.
(2009), "Protective Effects of Resilient Factor Derived from Fresh Water-grown Algae Chlorella on UVC-induced Cytotoxicity." BTS Autumn Meeting 2009, Durham, 英國.
(2010), "Prevention of activated macrophage-induced adhesion molecules by Chlorella extract in endothelial SEVC cells." 78th Eurapean Atherosclerosis Society congress, 漢堡Hamburg, 德國.
(2010), "Alleviatory effects of chlorella-derived polypeptides against UVB-induced MMP-1 expression and extracellular matrix degradation in human skin fibroblast cells." XIIth International Congress of Toxicology, 巴塞隆納, 西班牙.
(2011), "Prevention of activated macrophage-induced adhesion molecules by Chamaecyparis leaf extract in SEVC cells." 第26屆生物醫學聯合學術年會, 台北, 台灣.
(2011), "Lercanipine inhibits TNF-a production and attenuates vascular inflammation induced by lioppolysaccharide/interferon-gamma inhibition of NK-kB activation." 第26屆生物醫學聯合學術年會, 台北, 台灣.
(2011), "The potential genotoxicity of the flower of areca Catechu extracts in the SD rats." 第26屆生物醫學聯合學術年會, 台北, 台灣.
(2011), "Preventive effects of Chlorella on LPS-induced inflammation and septic death in mice." 10th World Congress of Inflammation, 巴黎, 法國.
J.-Y. Cherng, L.-C. Chen, S.-F. Liou, C.-L. Chen, S.-J. Chen, Mei-Fen Shih(2012), "Amelioration of activated macrophage-induced adhesion molecules production in endothelial SEVC cells and endothelial permeability by Chlorella-11 peptide." 80th European Atherosclerosis Society Congress, 米蘭, 義大利.
Mei-Fen Shih She.-Fen. Liou, Su-Jong Chen, Lei-Yi Chen, Shu-Ching Luo(2013), "Prevention of macrophage-induced adhesion molecules production and endothelial permeability in SEVC endothelial cells by Sporopollenin." 37th Congress of the International Union of Physiological Sciences, Birmingham, 英國.
施美份 、陳蕾伊 、羅舒清 、 陳素容(2013), "Alleviation of proinflammatory cytokine-induced adhesion molecule and endothelin-1 expression by Sporopollenin." 第28屆生物醫學聯合學術年會, 台北, 台灣.
李芝綺、鄭涵勻、施美份(2014), "Immunomodulatory effects of fresh water grown green algae on IL-12 and IL-10 production in macrophage and LPS-induced sepsis." 2014年台灣藥學會年會暨學術研討會, 高雄, 台灣.
陳素容、施美份(2014), "Ameliorating effects of Chlorella protein on glucose tolerance test and serum insulin and adipocytokines levels in STZ diabetic rats." 2014年台灣藥學會年會暨學術研討會, 高雄, 台灣.
M-F Shih 1, S-F Liou1, C-L Chen, & J-Y Cherng(2015), "Dunaliella salina modulates the adhesion molecules of endothelia and the cell migration of vascular smooth muscles to ameliorate inflammatory responses." 17th INTERNATIONAL SYMPOSIUM ON ATHEROSCLEROSIS, 阿姆斯特丹, 荷蘭.
J. Y. Cherng & M. F Shih(2015), "Induction of MMP-2 and MMP-9 expressions in aorta vascular smooth muscle cells through MAPK pathway by di(2-ethylhexyl)phthalate (DEHP)." 17th INTERNATIONAL SYMPOSIUM ON ATHEROSCLEROSIS, 阿姆斯特丹, 荷蘭.
陳素容、施美份(2015), "Prevention of activated macrophage-induced adhesion molecules by beta-thujaplicin in endothelial cells." 2015台灣藥學會年會暨學術研討會, 台南, 台灣.
施美份(2015), "Ameliorative Effects of Chlorella Protein on insulin resistance in 3T3-1 adipocytes." 2015台灣藥學會年會暨學術研討會, 台南, 台灣.
施美份(2015), "Possible mechanisms of di(2-ethylhexyl) phthalate (DEHP)-induced MMP-2 and MMP-9 expression and sell migration in rat A7r5 aorta vascular smooth muscle cells." 2015 young and leading Material Sciences conference, 三亞, 大陸.
M-F Shih, J-Y Cherng(2016), "Potential protective effects of Dunaliella salina on DEHP-induced MMP-2 and MMP-9 expression via MAPK, ERK1/2, Akt, and NF-kB pathways in vascular smooth muscle cells." 84th European atherosclerosis Society 2016, Innsbruck, 奧地利.
Su-Jong Chen (陳素容)、Chiu-Lan Chen (陳秋蘭)、Hui-Mei Yu (游慧美)、Mei-Fen Shih (施美份)(2016), "Preventive effects of Crodyceps extract on UVA and UVB –induced MMP-1 expression and activity in skin fibroblasts." 105年度台灣藥學年會暨學術研討會, 台北, 台灣.
Mei Fen Shih, Su Jong Chen, Chiu Lan Chen, Hui Mei Yu(2017), "Inhibitory effects of Cordyceps extract on UV-induced MMP-1 expression and degradation of collagen." 13th World Congress of inflammation, 倫敦, 英國.
Mei-Fen Shih & Jong Yuh Chern(2017), "Protective effects of Dunaliella against to suppression of co-administration of ethanol and DEHP on glutathione peroxidase activity and total antioxidative capacity in HepG2 Cells." 13th World congress of Inflammation, London, UK.
Jong Yuh Cherng, Su Jong Chen, Shu-Yang Yen, Mei Fen Shih(2018), "Inhibitory effects of Dunaliella salina on tyrosinease activity and melanin production in melanoma cells." 18th World Congress of Basic and Clinical Pharmacology 2018, 京都, 日本.
陳秋蘭、盛夢徽、施美份、劉淑芬(2018), "數位學習課程提升 學習動機 與學習成效." 第一屆台灣藥學聯合學術研討會, 台南, 台灣.
Jong Yuh Cherng, Su Jong Che2, Shu-Yang Yen, Mei Fen Shih(2018), "Inhibitory effects of Dunaliella salina on tyrosinease activity and melanin production in melanoma cells." 18th World Congress of Basic and Clinical Pharmacology 2018, 京都, 日本.
Yu-Cheng Dung; Su Jong Chen; Mei Fen Shih(2019), "Preventive effects of Cordyceps extract on vascular smooth muscle cells migration and expressions of MMP-2 and MMP-9 in responding to DEHP induction." 2019 IEEE Eurasia Conference on Biomedical Engineering, Healthcare and Sustainability, 沖繩, 日本.
許州億、施美份(2022), "建立統合分析系統應用於藥物預測開發及預估藥物進入人體試驗可行性之研究." 第五屆台灣藥學聯合學術研討會, 台北, 台灣.
Yi-Lien Liu, Chih-Hung Cheng, Mei-Fen Shih(2023), "Progression of Integrated Medication Safety by Community Pharmacists in Taoyuan City." 2023 29th FAPA Congress 亞洲藥學年會, 台北, 台灣.
專書, 解剖生理學 第13章消化系統, 華格那, 2012年04月出版(ISBN 978-986-6115-93-6).
王健珍、王慧虹、沈家瑞、施美份、殷本惠、張立青、陳秋蘭、程中玉、劉昭麟、劉淑芬、鍾渙、嚴錦城, 藥理學原理, 藝軒圖書出版社, 2015年03月出版(ISBN 978-957-616-998-4).
王姿文,林雅菁,施美份,程中玉,程淑惠,黃大駿,鄭蕙玲,賴柏琦, 生物學, 歐亞書局有限公司, 2015年04月出版(ISBN 978-976-280-2921-2).
程中玉、施美份、程淑慧、林雅菁、賴博琦、王姿文、鄭惠玲、黃大駿、葉旭華, 生物學, 歐亞書局有限公司, 2018年06月出版(ISBN 978-986-95042-8-7).
吳求淳、連文彬、林自勇、鄭麗菁、蔡佳蘭、隋安莉、陳瑩玲、陳秀珍、楊舒如、賴明德、施美份、黃桂祥、辛和宗, 解剖生理學二版, 華格那, 2021年07月出版(ISBN 978-986-362-776-0).
吳求淳、連文彬、林自勇、沈怡伶、鄭麗菁、蔡佳蘭、隋安莉、陳瑩玲、陳秀珍、楊舒如、賴明德、施美份、黃桂祥、辛和宗, 實用解剖生理學, 華格那, 2023年10月出版(ISBN 978-626-681-004-4).
研究計畫開發新陽離子型聚亞胺高分子Poly(aminoimine) (PAI)和PLL-imine-PEI (PLIP)作為生物分解性之基因載體並測試其傳遞Oct4及SirT1基因以緩和視網膜老化的應用研究
比較二氫啶類鈣離子通道阻斷劑在脂多醣體/干擾素-γ處理的細胞及內毒素血症小鼠對誘發性一氧化氮合成、基質金屬蛋白酵素的表現與HMGB1釋放的作用
台北市立醫院101年計畫案
以氣相層析分析綠藻(C. pyrenoidosa)對於塑化劑DEHP之吸附作用和以in 以氣相層析分析綠藻(C. pyrenoidosa)對於塑化劑DEHP之吸附作用和以i
比較1,4-dihydropyridine結構的鈣離子阻斷藥物在光照過程中的不穩定程度;以及分析它們和維生素C交互作用產生的新穎化合物在(1)鈣離子阻斷活性上的改變與在(2)抑制動脈粥樣化活性上的潛力
SGLT-2抑制劑在代謝症候群患者及大鼠調控心臟再塑性之功效-從臨床到基礎研究
培育女性研發人才在芝麻粕之生物轉化加值應用
培育女性研發人才在芝麻粕之生物轉化加值應用研究
計畫主持人開發可應用於化妝品的抗皮膚老化之成份及研究其分子作用機轉
Investigation of in vitro neuron protective effects of
防治藥物濫用社區認養計畫
開發可應用於化妝品的抗皮膚老化之成分及研究其分子作用機轉(∥)
探討淡水生綠藻萃出物於延緩光照皮膚老化的應用及生物分子原理
探討微藻對糖尿病動物之血糖改善功效
蛹蟲草抗UV引起皮膚老化及美白功效試驗委託計畫
藥學系教師實務及師生學術促進產學合作案
促進藥學系師生學術及教師實務能力之產學合作案
106年度第一期台北地區藥學系研究所碩士學分班
Piperacillin及sulbactam分析方法確認
06年度第2期台北地區藥學系研究所碩士學分班
107年度第1期大台北地區藥學系研究所碩士學分班
107年度第1期大桃園地區藥學系研究所碩士學分班
增進社區藥局學術能力之產學計畫案
強化藥學系師生學術及教師實務能力之產學合作案
提升藥理學院師生學術及教師實務能力之產學合作案
110年度第1期大台北地區藥學系研究所碩士學分班
芝麻粕之生物轉化\研究
111年度第1期大台北地區藥學系研究所碩士學分班
芝麻紿之生物轉化加值應用研究-子計畫芝麻紿發酵液美白活性應用
強化藥學系師生研究及實務能力—利用芝麻粕發酵產物探究抗發炎及在預防動脈粥樣化應用
專業證照行政院衛生署 "藥師證書" ()
考試院考選部,行政院衛生福利部(衛生署) "專門職業及技術人員考試 - 藥師" (1988/02/05)
榮譽教育部103 年度第2 梯次數位學習教材認證
第八屆藥理學院師生研究發表會 藥學系大學部壁報組第一名
第七屆藥理學院師生研究發表會 藥學系大學部壁報組第三名
第十屆藥理學院師生研究發表會 藥學系大學部壁報組第二名
教學卓越教師
Professional vocabulary Quotient credential In medical & nursing Professional terminology
2018上研機器人創意與創新競賽
106學年度教師評鑑成績優異
107學年度產學合作業務績效特優教師頒獎
106學年產學績效優良
Best conference paper reward
第14屆藥理學院師生研究發表佳作
第15屆藥理學院師生研究發表第3名
第15屆藥理學院師生研究發表佳作