姓名劉淑芬
職稱教授
聯絡電話 
電子郵件shufen2139@mail.cnu.edu.tw
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期刊論文(2009), "Inhibition of human prostate cancer cells proliferation by a selective alpha1-adrenoceptor antagonist labedipinedilol-A involves cell cycle arrest and apoptosis.." Toxicology, 256, 1-2. (SCI)
(2009), "Lercanidipine inhibits vascular smooth muscle cell proliferation and neointimal formation via reducing intracellular reactive oxygen species and inactivating Ras-ERK1/2 signaling.." Pharmacological Research, 59, 1. (SCI)
(2007), "Eugenosedin-A amelioration of lipopolysaccharideinduced up-regulation of p38 MAPK, inducible nitric oxide synthase and cyclooxygenase-2.." J Pharm Pharmacol, 59, 6. (SCI)
(2008), "Isoeugenodilol inhibits smooth muscle cell proliferation and neointimal thickening after balloon injury via inactivation of ERK1/2 pathway." Journal of Biomedical Science, 15, 3. (SCI)
(2006), "Inhibition of pro-inflammatory TNFα-induced iNOS by xanthine-based KMUP-1 and KMUP-3 in rat trachea: the involvement of soluble guanylate cyclase and protein kinase G.." Mol Pharmacol, 70, 3. (SCI)
(2006), "Protective effect of labedipinedilol-A, a novel dihydropyridine-type calcium channel blocker, on myocardial apoptosis in ischemia-reperfusion injury.." Life Science, 79, 13. (SCI)
(2005), "Labedipinedilol-C: a third-generation dihydropyridine-type calcium channel antagonist displaying K+ channel opening, NO-dependent and adrenergic antagonist activities.." Journal of Cardiovascular Pharmacology, 46, 2. (SCI)
(2005), "Increased circulating big endothelin-1, endothelin-1 and atrial natriuretic peptide in infants and children with failure secondary to congenital heart disease.." International Journal of Cardiology, 104, 1. (SCI)
(2005), "The vasorelaxing action of labedipinedilol-A involves endothelial cells-derived NO and eNOS expression caused by calcium influx.." Journal of Cardiovascular Pharmacology, 45, 3. (SCI)
(2008), "Effects of Labedipinedilol-A, Third-Generation Dihydropyridine-Type Calcium Blocker, on Ouabain-Induced Arrhythmia." Drug Development Research, 69, 無. (SCI)
(2010), "KMUP-1 attenuates isoprenaline-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways." British journal of pharmacology, 159, 5. (SCI)
(2010), "San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis Through eNOS and MAPK Pathways." Evid Based Complement Alternat Med, 2011, 無. (SCI)
(2011), "Protective effects of Chlorella-derived peptide on UVB-induced production of MMP-1 and degradation of procollagen genes in human skin fibroblasts.." Regulatory toxicology and pharmacology, 60, 1. (SCI)
(2011), "Labedipinedilol-A prevents lysophosphatidylcholine-induced vascular smooth muscle cell death through reducing reactive oxygen species production and anti-apoptosis.." Atherosclerosis, 217, 2. (SCI)
(2011), "Eugenolol and glyceryl-isoeugenol suppress LPS-induced iNOS expression by down-regulating NF-kappaB AND AP-1 through inhibition of MAPKS and AKT/IkappaBalpha signaling pathways in macrophages.." International journal of immunopathology and pharmacology, 24, 2. (SCI)
(2012), "San-Huang-Xie-Xin-Tang protects cardiomyocytes against hypoxia/reoxygenation injury via inhibition of oxidative stress-induced apoptosis." Journal of Natural of Medicines, 66, 2. (SCI)
Yeh JL, Hsu JH, Liang JC, Chen IJ, Liou SF.(2013), "Lercanidipine and labedipinedilol--A attenuate lipopolysaccharide/interferon-γ-induced inflammation in rat vascular smooth muscle cells through inhibition of HMGB1 release and MMP-2, 9 activities.." Atherosclerosis., 226, 2. (SCI)
Liou SF, Hsu JH, Lin IL, Ho ML, Hsu PC, Chen LW, Chen IJ, Yeh JL.(2013), "KMUP-1 Suppresses RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss: Roles of MAPKs, Akt, NF-κB and Calcium/Calcineurin/NFATc1 Pathways.." PLoS One, 8, 7. (SCI)
Hsu JH, Liou SF(劉淑芬), Yang SN, Wu BN, Dai ZK, Chen IJ, Yeh JL, Wu JR.(2014), "B-type natriuretic peptide inhibits angiotensin II-induced proliferation and migration of pulmonary arterial smooth muscle cells.." Pediatr Pulmonol, 49, 8. (SCI)
Chen HM, Liou SF(劉淑芬), Hsu JH, Chen TJ, Cheng TL, Chiu CC, Yeh JL.(2014), "Baicalein inhibits HMGB1 release and MMP-2/-9 expression in lipopolysaccharide-induced cardiac hypertrophy." Am J Chin Med, 42, 4. (SCI)
Chen HM, Hsu JH, Liou SF(劉淑芬), Chen TJ, Chen LY, Chiu CC, Yeh JL.(2014), "Baicalein, an active component of Scutellaria baicalensis Georgi, prevents lysophosphatidylcholine-induced cardiac injury by reducing reactive oxygen species production, calcium overload and apoptosis via MAPK pathways.." BMC Complementary and Alternative Medicine, 14, 233. (SCI)
Liou SF, Hsu JH, Chu HC, Lin HH, Chen IJ, Yeh JL.(2015), "KMUP-1 Promotes Osteoblast Differentiation Through cAMP and cGMP Pathways and Signaling of BMP-2/Smad1/5/8 and Wnt/β-Catenin.." J Cell Physiol, 230, 9. (SCI)
Liou SF, Hsu JH, Chen YT, Chen IJ, Yeh JL.(2015), "KMUP-1 Attenuates Endothelin-1-Induced Cardiomyocyte Hypertrophy through Activation of Heme Oxygenase-1 and Suppression of the Akt/GSK-3β, Calcineurin/NFATc4 and RhoA/ROCK Pathways.." Molecules, 20, 6. (SCI)
Wu JR, Hsu JH, Dai ZK, Wu BN, Chen IJ, Liou SF(劉淑芬, 通訊作者), Yeh JL(2016), "Activation of endothelial NO synthase by a xanthine derivative ameliorates hypoxia-induced apoptosis in endothelial progenitor cells.." Journal of Pharmacy and Pharmacology, 68, 6. (SCI)
Liu CP, Yeh JL, Liou SF(劉淑芬), Wu BN, Chen IJ.(2016), "Phosphodiesterase inhibitor KMUP-3 displays cardioprotection via protein kinase G and increases cardiac output via G-protein-coupled receptor agonist activity and Ca(2+) sensitization.." Kaohsiung Journal of Medical Sciences, 32, 2. (SCI)
Wu JR, Yeh JL, Liou SF(劉淑芬), Dai ZK, Wu BN, Hsu JH.(2016), "Gamma-secretase Inhibitor Prevents Proliferation and Migration of Ductus Arteriosus Smooth Muscle Cells through the Notch3-HES1/2/5 Pathway.." International Journal of Biological Sciences, 9, 12. (SCI)
Erna Sulistyowati , Ren-Long Jan , Shu-Fen Liou , Ying-Fu Chen, Bin-Nan Wu , Jong-Hau Hsu, Jwu-Lai Yeh(2020), "Vasculoprotective effects of Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction via the NOXs-ROS-NF-kB pathway in spontaneously hypertensive rats." Journal of Traditional and Complementary Medicine, 10, 0. (SCI)
Shu-Fen Liou, Thi Tuyet Ngan Nguyen, Jong-Hau Hsu, Erna Sulistyowati,Shang-En Huang, Bin-Nan Wu, Ming-Chung Lin and Jwu-Lai Yeh(2020), "The Preventive E ects of Xanthohumol on Vascular Calcification Induced by Vitamin D3 Plus Nicotine." Antioxidants, 9, 10. (SCI)
研討會論文(2008), "Labedipinedilol-A arrests cell cycle progression and induces apoptosis through activation of caspase-dependent and caspase-independent pathways in human prostate cancer cells.." The 23th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
(2008), "Cardioprotective effect of San-Huang-Xie-Xin-Tang on myocardial apoptosis in ischemia-reperfusion injury.." The 23th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
(2009), "Anti-inflammatory activities and mechanisms of triterpenoids and flavonoids isolated from Euphorbia Formosana in cells activated with lipopolysaccharide." The 24th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan.
(2009), "Anti-inflammatory evaluation and mechanisms of eugenol and isoeugenol derivatives in lipopolysaccharide-stimulated macrophages." The 24th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
(2009), "Protective Effect of KMUP-1 against ET-1-Induced Cardiac Hypertrophy in H9c2 Cells." 6th Metabolic Syndrome, type II Diabetes, and Atherosclerosis Congress, Berlin, Germany.
(2010), "Effect of α-Solanine on Cytotoxicity in Rat Cardiomyocytes And Vascular Smooth Muscle Cells." The 25th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan.
(2008), "Cyclic AMP mediates KMUP-3-induced positive inotropic activity, involving alteration of Rho-A/ROCK expression." The 23th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
(2008), "Anti-apoptotic role for KMUP-1 in stimulated ischemia-induced myocardial cell injury." The 23th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
(2008), "The role of nitric oxide regulating beta-adrenergic adenylate cyclase system plays in proliferation of kertinocyte." The 23th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
(2010), "Anti-inflammatory evaluation and mechanisms of eugenol and isoeugenol derivatives in lipopolysaccharide-stimulated macrophages." The XII International Congress of Toxicology, Barcelona, Spain.
(2009), "Anti-inflammatory Activity and Blockade of Nuclear Factor-κB Signaling Pathway of Triterpenoids and Flavonoids Isolated from Euphorbia Formosana." 第二十四屆天然藥物研討會, 高雄, 台灣.
(2010), "Phosphodiesterase 5 Inhibitors with Inducible Nitric Oxide Synthase Suppression and Endothelial Nitric Oxide Synthase-Enhancing Properties Attenuate Hypertensive Cardiomyopathy.." 3rd International Conference on Hypertension, Diabetes, Lipids and Stroke Prevention, 柏林, 德國.
(2011), "Lercanidipine inhibits TNF-α production and attenuates vascular inflammation induced by lioppolysaccharide/interferon-γ via the inhibition of NF-κB activation." 第26屆生物醫學聯合學術年會, 台北, 台灣.
(2011), "The xanthine derivative KMUP-1 inhibits osteoclastogenesis through modulation of NF-kB pathway." 第26屆生物醫學聯合學術年會, 台北, 台灣.
(2011), "The potential genotoxicity of the flower of areca catechu extracts in the SD rats." 第26屆生物醫學聯合學術年會, 台北, 台灣.
(2011), "Effects of extracellular heat shock protein on septic cardiomyopathy in rats." 第26屆生物醫學聯合學術年會, 台北, 台灣.
(2011), "Prevention of activated macrophage-induced adhesion molecules by Chamaecyparis leaf extract in SEVC cells." 第26屆生物醫學聯合學術年會, 台北, 台灣.
(2011), "Lercanidipine attenuates proinflammatory cytokines and vascular inflammation induced by lipopolysaccharide/interferon-r." 10th World Congress on Inflammation, 巴黎, 法國.
(2011), "Preventive effects of Chlorella on LPS-induced inflammation and septic death in mice." 10th World Congress on Inflammation, 巴黎, 法國.
(2011), "α-Solanine induces apoptosis in rat smooth muscle cells." 26th Symposium on Natural Products, 台中, 台灣.
(2012), "Labedipinedilol-A inhibits lysophosphatidylcholine-induced cell death in cultured primary rat aortic smooth muscle cells." 第27屆生物醫學聯合學術年會, 台北, 台灣.
(2012), "KMUP-1 promotes osteoblastic differentiation and mineralization through activation of the BMP/Runx-2 pathway." 第27屆生物醫學聯合學術年會, 台北, 台灣.
(2012), "The hepato-protective effect of cultured fruiting body of Cordyceps Militaris on mitomycin C-induced cytotoxicity." 第27屆生物醫學聯合學術年會, 台北, 台灣.
Liou Shu-Fen (劉淑芬), Shih Mei-Fen(施美份), Yeh Jwu-Lai (葉竹來)(2012), "Labedipinedilol-A inhibits lysophosphatidylcholine-induced cell death in cultured primary rat aortic smooth muscle cells." 80th European Atherosclerosis Society Congress, 米蘭, 義大利.
Shu-Fen Liou, Mei-Fen Shih, Chiu-Lan Chen(2013), "Lercanidipine and labedipinedilol-A play anti-inflammatory role through inhibition of lipopolysaccharide/interferon-γ-induced HMGB1 release and MMP-2, 9 activities in vascular smooth muscle cel." 37th Congress of the International Union of Physiological Sciences, Birmingham伯明罕, UK ( 英國).
Shu-Fen Liou, M.F. Shih, J.L. Yeh(2012), "Labedipinedilol-A inhibits lysophophatidylcholine-induced cell death in cultured primary rat aortic smooth muscle cells." 80th European Atherosclerosis Society, Milan (米蘭), Italy (義大利).
Shu-Fen Liou (劉淑芬), Chiu-Lan Chen, Mei-Fen Shih(2014), "The xanthine derivative KMUP-1 stimulates osteoblastogenesis through activating the BMP/Runx-2 signaling pathway." 5th FIP Pharmaceutical Sciences World Congress, 墨爾本, 澳洲.
劉淑芬, 葉竹來(2014), "KMUP-1 activates osteoblast differentiation through cAMP and cGMP pathways and signaling of BMP-2/Smad1/5/8 and Wnt/beta-catenin." 台灣藥學會年會暨學術研討會, 高雄, 台灣.
Shu-Fen Liou(劉淑芬), Chiu-Lan Chen(2015), "KMUP-3 protects cardiac fibroblasts from apoptosis induced by hydrogen peroxide through the adaptive autophagy." 17th INTERNATIONAL SYMPOSIUM ON ATHEROSCLEROSIS, 阿姆斯特丹, 荷蘭.
劉淑芬, 王菱誼,葉竹萊(2015), "Protection of cultured cardiac fibroblasts from hydrogen peroxide-induced apoptosis by a novel xanthine derivative." 2015台灣藥學會年會暨學術研討會, 台南, 台灣.
張瀞文、劉中平、劉淑芬、陳英俊、葉竹來(2016), "KMUP-3 Attenuates Vascular Smooth Muscle Cells Calcification and Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-Knockout Mice." 第31屆生物醫學聯合學術年會, 台北, 台灣.
Shu-Fen Liou(劉淑芬), Chih-Chieh Hsu, Jwu-Lai Yeh(2016), "KMUP-1, a derivative of xanthine, attenuates atherosclerosis formation in apolipoprotein E-knockout mice." The 10th Congress of the Asian-Pacific Society of Atherosclerosis and Vascular Diseases, 東京, 日本.
陳秋蘭、陳寶惠、涂逸權、劉淑芬(通訊作者)(2016), "因社區健保藥局藥師介入而增加第2型糖尿病患者服藥順從性及改善血糖控制之研究." 105年度台灣藥學會年會暨學術研討會, 台北, 台灣.
Shu-Fen Liou(劉淑芬), Li-Ying Chen(陳儷英), Chiu-Lan Chen(陳秋蘭)(2018), "Xanthohumol attenuates beta-glycerophosphate-induced vascular calcification by inhibiting osteoblastic differentiation." The 18th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY 2018, 京都, 日本.
張麗珍, 劉淑芬(2020), "Effect of xanthohumol on vascular calcification." 2020第二屆台灣藥學聯合學術研討會, 台北, 台灣.
張麗珍、劉淑芬(2021), "Effect of α-mangostin on vascular calcification." 第三屆臺灣藥學聯合學術研討會, 台南, 台灣.
Li-Chen Chang (張麗珍), Shu-Fen Liou(劉淑芬)(2022), "Xanthohumol prevents beta-glycerophosphate-induced calcification in cultured rat vascular smooth muscle cells." 第五屆臺灣藥學聯合學術研討會, 台北, 台灣.
劉淑芬、沈國屏(2024), "A prenylated flavonoid from hops prevents vascular calcification in rat aortic vascular smooth muscle cells." 第38屆JACBS 生醫聯合學術年會, 台北, 台灣.
專書王健珍、王慧虹、沈家瑞、施美份、殷本惠、張立青、陳秋蘭、程中玉、劉昭麟、劉淑芬、鍾渙、嚴錦城, 藥理學原理, 藝軒圖書出版社, 2015年03月出版(ISBN 978-957-616-998-4).
研究計畫網路醫學資訊判斷標準與可信性之研究
黃芩素及類似物對腹主動脈瘤和粥狀動脈硬化調節粒腺體動態和自噬作用的機轉探討
109年度精進新興生醫產品GTP符合姓管理制度之研析
計畫主持人Labedipinedilol-A對人類攝護腺細胞抑制增生及誘發細胞凋亡之機制探討
台灣大戟 (Euphorbia formosana) 之三類及黃酮類活性化合物對內毒素在體外及體內引起發炎之作用及分子機制研究
丁香醇和異丁香醇衍生物之體外細胞模式及體內內毒素模式之抗發炎活性評估與訊息傳遞路徑之探討
探討丁香醇和異丁香醇衍生物之體外對抗內毒素引起發炎反應及氧化壓力路徑之作用
新型二氫吡啶類鈣離子通過阻斷劑對血管平滑肌細胞以脂多醣體及干擾素-y誘發發炎的保護作用及其分子調控機制
比較二氫啶類鈣離子通道阻斷劑在脂多醣體/干擾素-γ處理的細胞及
岡山地區內科診所用藥諮詢及研究分析
探討山竹黃酮減少血管鈣化防止粥狀動脈硬化之分子機
黃腐醇對於大鼠血管鈣化之影響及其相關機轉研究
黃腐醇對實驗動物以維生素D3加尼古丁致心血管鈣化模式的影響
互動機器人於台南關廟某藥局之應用
專業證照行政院衛生署 "藥師證書" (1996/12/12)
考試院考選部,行政院衛生福利部(衛生署) "專門職業及技術人員考試 - 藥師" (1996/12/12)
考試院考選部,行政院衛生福利部(衛生署) "專門職業及技術人員考試 - 藥師" (1996/12/12)
榮譽藥學系大學部壁報組第三名
教育部數位學習認證
2015台灣藥學會年會暨學術研討會壁報論文競賽佳作